1-3
| 2-Phenyl-4(5)-[[4-(pyrimidin-2- yl)piperazin-1-yl]methyl]imidazole. A Highly Selective Antagonist at Cloned Human D4 Receptors
Andrew Thurkauf,
Jun Yuan,
Xi Chen,
Xiao Shu He,
Jan W. F. Wasley,
Alan Hutchison,
Kristine H. Woodruff,
Robin Meade,
Diane C. Hoffman,
Hilary Donovan, and
Deborah K. Jones-Hertzog
[Full Article -
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4-8
| Rationally Designed Inhibitors of Inosine Monophosphate Dehydrogenase
Han-Zhong Zhang,
Kotesvar Rao,
Stephen F. Carr,
Eva Papp,
Kenneth Straub,
John C. Wu, and
Josef Fried
[Full Article -
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9-17
| Synthesis and Characterization of Technetium-99m-Labeled Tropanes as Dopamine Transporter-Imaging Agents
Sanath K. Meegalla,
Karl Plössl,
Mei-Ping Kung,
Sumalee Chumpradit,
D. Andrew Stevenson,
Steven A. Kushner,
William T. McElgin,
P. David Mozley, and
Hank F. Kung
[Full Article -
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18-23
| Synthesis and Evaluation of 2-(Arylamino)imidazoles as  2-Adrenergic Agonists
Stephen A. Munk,
Dale A. Harcourt,
Premilla N. Arasasingham,
James A. Burke,
Alexander B. Kharlamb,
Cynthia A. Manlapaz,
Edwin U. Padillo,
Donald Roberts,
Eileen Runde,
Linda Williams,
Larry A. Wheeler, and
Michael E. Garst
[Full Article -
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24-34
| Cardioselective Antiischemic ATP-Sensitive Potassium Channel (KATP) Openers. 5. Identification of 4-(N-Aryl)-Substituted Benzopyran Derivatives with High Selectivity
George C. Rovnyak,
Syed Z. Ahmed,
Charles Z. Ding,
Steven Dzwonczyk,
Francis N. Ferrara,
W. Griffith Humphreys,
Gary J. Grover,
Dinos Santafianos,
Karnail S. Atwal,
Anne J. Baird,
Lee G. McLaughlin,
Diane E. Normandin,
Paul G. Sleph,and
Sarah C. Traeger
[Full Article -
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35-43
| Highly Selective, Novel Analogs of 4-[2-(Diphenylmethoxy)ethyl]- 1-benzylpiperidine for the Dopamine Transporter: Effect of Different Aromatic Substitutions on Their Affinity and Selectivity
Aloke K. Dutta,
Lori L. Coffey, and
Maarten E. A. Reith
[Full Article -
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44-49
| Synthesis and Anticonvulsant Activities of 3,3-Dialkyl- and 3-Alkyl-3-benzyl-2-piperidinones ( -Valerolactams) and Hexahydro-2H-azepin-2-ones (eps-Caprolactams)
P. Amruta Reddy,
Karen E. Woodward,
Sarah M. McIlheran,
Bonnie C. H. Hsiang,
Tammy N. Latifi,
Matthew W. Hill,
Steven M. Rothman,
James A. Ferrendelli, and
Douglas F. Covey
[Full Article -
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50-60
| Discovery of Potent Isoxazoline Glycoprotein IIb/IIIa Receptor Antagonists
John Wityak,
Thais M. Sielecki,
Donald J. Pinto,
George Emmett,
Jean Y. Sze,
Jie Liu,
A. Ewa Tobin,
Shuaige Wang,
Biao Jiang,
Philip Ma,
Shaker A. Mousa,
Ruth R. Wexler, and
Richard E. Olson
[Full Article -
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61-72
| Synthesis and in Vitro Activity of 3 -Substituted-3-hydroxypregnan-20-ones: Allosteric Modulators of the GABAA Receptor
Derk J. Hogenkamp,
S. Hasan Tahir,
Jon E. Hawkinson,
Ravi B. Upasani,
Mian Alauddin,
Catherine L. Kimbrough,
Manuel Acosta-Burruel,
E. R. Whittemore,
R. M. Woodward,
Nancy C. Lan,
Kelvin W. Gee, and
Michael B. Bolger
[Full Article -
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73-84
| 3-Hydroxy-3-(phenylethynyl)-5-pregnan-20-ones: Synthesis and Pharmacological Activity of Neuroactive Steroids with High Affinity for GABAA Receptors
Ravindra B. Upasani,
Kevin C. Yang,
Manuel Acosta-Burruel,
Chris S. Konkoy,
James A. McLellan,
Richard M. Woodward,
Nancy C. Lan,
Richard B. Carter, and
Jon E. Hawkinson
[Full Article -
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85-91
| Synthesis and Evaluation of Trimetoquinol Derivatives: Novel Thromboxane A2/Prostaglandin H2 Antagonists with Diminished -Adrenergic Agonist Activity
Jeffrey J. Christoff,
Luke Bradley,
Duane D. Miller,
Longping Lei,
Fernando Rodriguez,
Paul Fraundorfer,
Karl Romstedt,
Gamal Shams, and
Dennis R. Feller
[Full Article -
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92-98
| Threonine6-Bradykinin: Structural Characterization in the Presence of Micelles by Nuclear Magnetic Resonance and Distance Geometry
Maria Pellegrini,
Stefano Mammi,
Evaristo Peggion, and
Dale F. Mierke
[Full Article -
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99-104
| Threonine6-Bradykinin: Molecular Dynamics Simulations in a Biphasic Membrane Mimetic
Maria Pellegrini and
Dale F. Mierke
[Full Article -
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105-111
| Antirheumatic Agents: Novel Methotrexate Derivatives Bearing a Benzoxazine or Benzothiazine Moiety
Hiroharu Matsuoka,
Nobuhiro Ohi,
Masahiko Mihara,
Hiroshi Suzuki,
Katsuhito Miyamoto,
Noriaki Maruyama,
Keiichiro Tsuji,
Nobuaki Kato,
Toshio Akimoto,
Yasuhisa Takeda,
Keiichi Yano, and
Toshio Kuroki
[Full Article -
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112-116
| Chemical and Biological Studies on a Series of Novel (trans-(1R,2R)-, trans-(1S,2S)-, and cis-1,2-Diaminocyclohexane)platinum(IV) Carboxylate Complexes
Abdul R. Khokhar,
Salam Al-Baker,
Shaikh Shamsuddin, and
Zahid H. Siddik
[Full Article -
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117-124
| Stereoselective Synthesis and Biodistribution of Potent [11C]-Labeled Antagonists for Positron Emission Tomography Imaging of Muscarinic Receptors in the Airways
Ton J. Visser,
Aren van Waarde,
Twan J. H. Jansen,
Gerben M. Visser,
Thom W. van der Mark,
Jan Kraan,
Kees Ensing, and
Willem Vaalburg
[Full Article -
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125-131
| Diltiazem-like Calcium Entry Blockers: A Hypothesis of the Receptor-Binding Site Based on a Comparative Molecular Field Analysis Model
Federico Corelli,
Fabrizio Manetti,
Andrea Tafi,
Giuseppe Campiani,
Vito Nacci, and
Maurizio Botta
[Full Article -
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132-136
| Mixed Bis(thiosemicarbazone) Ligands for the Preparation of Copper Radiopharmaceuticals: Synthesis and Evaluation of Tetradentate Ligands Containing Two Dissimilar Thiosemicarbazone Functions
John K. Lim,
Carla J. Mathias, and
Mark A. Green
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